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5 Largest Family Office Direct Deals of September 2025

Family offices continue to be powerful drivers of innovation, directly funding next-generation companies across AI, biotech, infrastructure, and more. Using verified FINTRX family office data, we spotlight five of the largest direct investments from September 2025, revealing where ultra-wealthy investors are placing their capital and which founders are capturing their attention.


1. Anthropic Raises $13B Series F Co-Led by ICONIQ Capital Family Office

Anthropic, the fast-growing AI research company rivaling OpenAI and Cursor, raised a staggering $13 billion in Series F financing. The round was co-led by ICONIQ Capital (family office arm), alongside Fidelity Management and Lightspeed Venture Partners, pushing Anthropic’s valuation to $183 billion. The deal included a deep syndicate of global investors, underscoring the market’s belief in foundational AI technologies.

• Deal Size: $13B
• Company: Anthropic
• Investors: ICONIQ Capital Family Office (co-lead), Fidelity Management, Lightspeed, Blackstone, Baillie Gifford, BlackRock, and more
• Sector: Artificial Intelligence

View ICONIQ Capital Family Office in FINTRX

 

2. Sierra Lands $350M with ICONIQ Capital Family Office Backing

Founded by ex-Salesforce Co-CEO Bret Taylor, Sierra is building AI agents for customer service, automating high-value, human-like support. The $350 million round was led by Greenoaks Capital, with ICONIQ Capital participating as a strategic investor. Sierra has achieved a $10 billion valuation in under two years.

Deal Size: $350M
Company: Sierra
• Investors: ICONIQ Capital Family Office (participant), Greenoaks Capital (lead), Thrive Capital
Sector: AI / Customer Service Automation

View ICONIQ Capital Family Office in FINTRX

 

3. Kriya Therapeutics Secures $320M Co-Led by Premji Invest

Gene therapy innovator Kriya Therapeutics raised $320 million in Series D funding to further develop novel treatments for chronic diseases. Premji Invest (Azim Premji Family Office) co-led the round alongside Patient Square Capital. Thiel Capital (Peter Thiel Family Office) also joined the syndicate as a non-lead investor.

Deal Size: $320M
Company: Kriya Therapeutics
Investors: Premji Invest (Azim Premji), Thiel Capital (Peter Thiel), Patient Square Capital, Narya Capital, The T1D Fund
Sector: Gene Therapy / Pharma Tech

View Premji Invest in FINTRX
View Thiel Capital in FINTRX

 

4. Periodic Labs Raises $300M in Seed Round Backed by Bezos & Schmidt Family Offices

Periodic Labs, founded by AI veterans from OpenAI and DeepMind, emerged from stealth with a massive $300 million seed round. Their aim? To build an “AI scientist” capable of automating the scientific discovery process. Hillspire LLC (Eric Schmidt Family Office) and Bezos Expeditions (Jeff Bezos Family Office) joined an elite group of early backers.

Deal Size: $300M
Company: Periodic Labs
Investors: Hillspire LLC (Eric Schmidt), Bezos Expeditions (Jeff Bezos), Andreessen Horowitz, DST, Nvidia, Accel
Sector: AI / Scientific Discovery

View Hillspire LLC (Eric Schmidt Family Office) in FINTRX
View Bezos Expeditions (Jeff Bezos Family Office) in FINTRX

 

5. Modular Raises $250M Series C Led by Tulco (Thomas Tull Family Office)

Modular, an AI infrastructure startup aiming to streamline AI deployment and performance, raised $250 million in Series C funding. The round was led by Tulco, LLC (Thomas Tull Family Office), with participation from DFJ Growth, GV (Google Ventures), Greylock, and General Catalyst. The company is now valued at $1.6 billion.

• Deal Size: $250M
Company: Modular
Investors: Tulco, LLC (Thomas Tull), DFJ Growth, Google Ventures, Greylock, General Catalyst
Sector: AI / Infrastructure

View Tulco, LLC (Thomas Tull Family Office) in FINTRX

 

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Disclaimer: This content is for informational purposes only and should not be interpreted as investment advice or a recommendation to invest in any company, security, or strategy mentioned.


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